Tramadol Effective on Opioid Withdrawal Symptoms

Tramadol Effective on Opioid Withdrawal Symptoms

The extended-release (ER) formulation of tramadol was shown to be as effective as buprenorphine and more effective than clonidine for treating symptoms of opioid withdrawal, in a study published in JAMA Psychiatry.1 The use of clonidine and buprenorphine in supervised withdrawal treatment of patients with opioid use disorder (OUD) is complicated by several factors. Clonidine may cause sedation and hypotension, requires multiple doses per day and is not as effective as opioid agonists in..

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